Best of luck to ya and I hope your next cycle proves 'the one'!!! So we didnt biopsy & test then freeze. How are you feeling? 150 iu follistim and 75 iu menopure didn't work either. 3 failed IUI's ODWU revealed blocked tube(s). My little one is a success story from MDL! Who has had success switching to a different protocol, specifically on your 2nd round? Create an account or log in to participate. I started with an estrogen patch every other day then on saturday started cetrotide injections for 3 consecutive days. We got pregnant with my first IUI, but miscarried within 2 weeks. I see a lot of people have taken Lupron. IVF Cycle #5 | Microdose Lupron Flare Protocol | Low AMH 2,095 views Feb 5, 2022 64 Dislike Share Tiana Smith 1.24K subscribers Hello All! Instead, we've had two "highly unusual" experiences and I could really use some input. At 43 I see now looking back it truly is egg quality. The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to support the lining. The short protocol also known as microdose or flare protocol takes advantage of the body's initial response to Lupron with a surge of hormones for several days that stimulates the ovaries. Hopefully they know what they're doing! Some of these involve the use of oral medications, such as Clomid or Femara in addition to gonadotropins. Use of this site is subject to our terms of use and privacy policy. Switch Protocol 2nd Time Around? And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). 1 single dose LUPRON-at RE office Suite 1200 I'm starting IVF#3 on November 14th. In patients with low egg reserve, this combination may exert . Objective: To compare the effect of the GnRH antagonist/letrozole protocol (AL) with the microdose GnRH agonist flare-up (MF) protocol in poor ovarian responders for intracytoplasmic sperm injection (ICSI). Start Lupron: Start your microdose Lupron 20 units subcutaneous injection twice a day. Multiple research studies have compared IVF agonist and antagonist protocols with most showing similar pregnancy rates. 0000017388 00000 n Of the 11 eggs that fertilizedsuccessfully across the 3 cycles, we had 9 of them make it to blastocysts and got 4 chromosomally normal embryos. I know I did Gonal-F because I'd never done it before (I was a follistim lady prior) - I can check tonight and see what it was. DH and I have been TTC for 4.5 years or so: Three days following the last OCP, lupron 20 mcg b.i.d. The LDL protocol was initiated with late luteal lupron (0.25 mg daily). I don't fit into either of those categories, but I am excited to try a different protocol. Lots of failures (8 embryos didn't implant - mostly FET) and 1 success - we have a 3 year old son from a fresh IVF. 2005-2023Everyday Health, Inc., a Ziff Davis company. Earnest Letter. 13R. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Dont get discouraged. I would like to know if any has been on the EPP/ MDL protocol ? We retrieved 4 eggs. 08/20 - Injection #2 Reply with more details about your situation and I'm sure other gals on the site here will respond with their advice more specific to your situation. . i.really hope.that this year brings me some.good.news..thanks.for sharing your story. 16dp5dt. I did estrogen priming with no BCP for this cycle (in addition to several other changes). Are you sure you want to block this member? I just pray it works. If so, I'd love to hear thoughts/experiences. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. This is the first step of the Microdose Lupron IVF Protocol for just the Lupron injection. i will try to check back.. i actually have a little extra orlissa, in case you'd like me to send it to you? As stated above, this protocol is the most commonly used regimen, both in the US and in our practice. I am sure of it! I did microdose Lupron flare protocol for my first cycle back in August. Women with high LH or FSH levels, decreased ovarian/egg reserve and a history of prior poor response to ovarian stimulation benefit the most from such a protocol. They are giving three more days on stimming before making the call. Only one embryo ever implanted (first cycle) and it resulted in a MMC. Er 4: sep 2020 - same protocol as er3 but with estrogen priming - ovulated all before retrieval. Beta2 9/12: 378! During the first two cycles I was on F, Hi Ladies, my current IVF cycle @ccrm got converted to a freeze-all due to high p4 and e2 levels. my clinic doesnt do growth hormone which Ive always heard good things about it. Please!!!!!!!!!!!!! Like usually day 17 or something. Foll, and Meno. My cycle "might" be cancelled. BFP on FRER 5dp5dt: IN SHOCK! Following. We won't necessarily see him for every appointment because of scheduling, but he will be the person we consult on what to do/ he will be helping us make all the decisions moving forward. Create an account or log in to participate. does your doctor use a medication called "orlissa" ? I've done microdose lupron flare protocol for the past two IVF cycles and the return has been CONSIDERABLY better than IVF#1 (antagonist protocol, 4 eggs retrieved, I cried). So- that's what's going on. The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to Apparently we waited too long ? I did get 4 chromosomally normal embryos from 3 cycles (we did PGS on day 6 blasts). Doc said it was odd and confusing why that last cycle was such a winner so again, may have been just lucky. Use of this site is subject to our terms of use and privacy policy. Any help would be greatly appreciated looking for hope this time around.. Hi everyone, does anyone have any thoughts on which protocol is better for older women and which protocol is best for retrieving good quality, chromosomally normal eggs? Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. IVF # 1 (flare protocol) Cancelled (poor response) 2010 IVF # 1 (2nd attempt)-microdose flare/estrogen priming BFP! But as I said.. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. Anyway, I am doing the EPP this round and was curious to hear some of your experiences with it. Er2: 7 mature eggs, follistim 250 iu with ganirelix, no priming. Right now, they are doing an antagonistic approach. 0000002646 00000 n We also added microfluidics to our last two cycles, you can check out the Zymot chip and ended up with twice the number of embryos that made it to blast. i actually have a little extra orlissa, in case you'd like me to send it to you? While some practices make a big deal over the choice of gonadotropin (some use only recombinant FSH, such as Gonal F or Follistim while others primarily use urinary hMG drugs such as Bravelle or Menopur), most studies suggest that there is very little if any difference in pregnancy rates between the different medications. 0000002919 00000 n Thanks all, I really appreciate all of you in this forum. I do have DOR and Endo, Amh 0.69. afc and fish comparable to yours or slightly worse. Beta3 9/14: 1224! I have a normal AMH for my age but I've read this protocol is for DOR or poor responders. The eggs are weaker as we get older and in turn weaker embryos. What was your protocol before? IVF#4 (Dec2013/Jan 2014): Microdose flare+Saizen+testosterone 4 eggs retrieved, all mature and fertilized by ICSI, ET of 1 6-cell embryo an 1 8-cell embryo graded 2 and 3. Previous studies comparing E2 priming and leuprolide flare IVF protocols report that E2 priming protocols result in longer cycles and higher total gonadotropin dose with similar oocyte yield, fertilization, and pregnancy rates; though, one report suggests a trend toward higher quality embryos in E2 priming cycles. So now we are dealing with issues on my side and i'm only 26 years old. 2nd U/S @ 7w2d. I had elevated anticardiolipins. I like my current doctor. On the other hand, the Long Agonist protocol can't use Lupron as the trigger because it already deploys Lupron elsewhere. undefined will no longer be visible to you including posts, replies, and photos. An extremely challenging and embryo transfer were to microdose lupron. Treatment history: 31F/29M, 0.9 AMH, 10 FSH, 6-12AFC, mild LPD/dysfolliculogenesis/unexplained. However other had mature egg and we did Icsi by it didn't grow from there. me 33/DH 36ttc since 10/2008; d/x: mild MFI, stageII endo~~PAIF/SAIF Welcome~~11 IUIs = 1 m/c (7w4d)IVF#1 January 2012 BFN, FET #1 April 2012 BFNSurprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160Stick Frogger Stick! I tried IVF in may since my follicle count was low I cancelled it. Then on stimming day 6, they found 18 follies. Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? I really believe that its a miracle protocol for those who are poor responders. First ivf was luteal lupron protocol. He is suggesting microdose lupron flare with GH. Lazer T, Liu A, et al. This typically takes 8-12 days, during which time the stimulation is monitored using a combination of vaginal ultrasound and a blood estrogen level approximately every 2-3 days. Guessing my trigger will be on 10/1. But I'll let you know if I respond better! 0000002254 00000 n I'm about to start a ton of supplements my nurse suggested to me. Instead we are doing estrogen priming followed by microdose lupron. I hate long stims. Find other members in this community to connect with. As access age, Tarlatzis BC. I'm very puzzled as why my RE will recommend something that could potentially cause my c, Hi ladies, Estrogen Primed Microdose Lupron Flare Protocol. <<7e73b458605e884a9eec5f5e9aeedda8>]>> Amazing! They also recently found scarred tissue on my lining. We've been trying for 3 years. Both my l, Short protocol or long protocol for older women. Now Im on a flare protocol and Im on day Is an immune protocol actually working for me? My anatogist cycle sucked. Any success stories for low responders of Estrogen Priming cycle? Anyone have good success? Four mature eggs were retrieved. Bzeety & Hootie- you guys give me sooo much hope, seeing that you both had success with this protocol after being through the ringer so many times. The example above shows 9 days of stimulation (FSH shots). Been feeling lonely lately as friends and family are getting pregnant around me (even friends who also struggled with fertility issues), so looking for somewhere else to hopefully find people to connect with. Afte, Hi all, Femara-Antagonist Protocol. trailer I'm praying this protocol will be successfull for us. Doc consult at the end of this month. For those women whove had more than one ivf cycle, did you change protocol? The Antagonist protocol uses Lupron as its trigger, rather than hCG, and Lupron's properties dramatically lower the risk a woman will hyperstimulate. So Im not sure how that changes for you, since you were able to get eggs. Anyone done this protocol? Did they give you a plan for your cycle yet? 600mg Ibprofin(sp?) Two different clinics. 8 fertilized w/ IC, Im about to do a frozen embryo transfer but I have very thin uterine lining. Initial was 12. Only got 1 mature egg and embryothat didnt make it. were initiated in patients receiving MDF. An EPP for you. Started with our current RE in April 2017; diagnosis is unexplained infertility (everything came back fine for both me and my husband on all tests). Then it'll be a flare approach, but Dr C said I would still be on a high dose with meds. Hi ladies,My RE proposed for my IVF#5 the micro flare protocol with BCP priming. Any input / thoughts are greatly appreciated! Has anyone used this protocol and had any success? Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. S:\Medical Forms\IVF Forms\Microflare Protocol\03-21-06 Sunday Gonadotropin Cycle Start MICRO-DOSE LUPRON FLARE PROTOCOL Sunday Monday Tuesday Wednesday Thursday Friday Saturday OCP's: Ortho Novum 1/35 (continue for 2-3 weeks) Baseline Sonogram Take Last OCP Lupron 0.2 cc 2 times each day until HCG Stimulation medication start I took BCP for 3 weeks. Called GnRH antagonists, these medications work differently than the GnRH agonists like Lupron. I'm team lupron flair for life. Is this normal??? It seems to be less common, since most clinics batch cycle, and this one is based off your individual cycle. Are you sure you want to block this member? My personal opinion is that even though I have read over and over again that it is a DOR / poor responder protocol, the people I seem to see having success with it are not really in that category. Stage IV Endo. Had two follicles but one disappeared day of egg retrieval. puffiness or swelling of the eyelids or around the eyes. 0000000960 00000 n Estrogen Priming Protocol: In some women who respond poorly to the short protocol (e.g., women diagnosed with Diminished Ovarian Reserve (DOR)), this protocol may enhance ovarian response, perhaps by synchronizing more follicles for recruitment and retrieval. - Estrogen patch 14 days, prio, Hi all, some people think that a bcp suppresses some women too much and so a epp is used instead. [Sheri] What is DHEA? Seven cycles were cancelled with no response - some after more than 2 weeks of stim. Any success stories ? skin rash, hives, or itching. ", Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN, ET 9/14 2 embies transferred. Non left to freeze --> BFN IVF#5 (April/May 2014): Antagonist Estrogen Priming -Cornell Protocol (Clomid+ Menopur+Gonal F + Orgalutran) Hello! 39 year old multiple failed cycles need advice. END MENTS. xref Have questions about navigating your Inspire support community or need assistance from one of our Inspire Moderators? Please specify a reason for deleting this reply from the community. 6500 N. Mopac (Loop 1) Expressway Building 1, I recently suffered a miscarriage at 7 weeks. I'm 36 & TTC 2 yrs. Had 19 follicles on my baseline, which was really good for me, but I ended up with 4 large follicles . My dr wants the lining to be between 8-12. sometimes a bcp is used for this same purpose. What my clinic is proposing, however, is starting. Thanks! If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. Issues on my side and I could really use some input turn weaker embryos had any success egg... Giving Three more days on stimming day 6, they are giving more. Low I cancelled it success story from MDL instead, we 've two! Highly unusual '' experiences and I have very thin uterine lining only got 1 mature egg and we PGS. Said I would still be on a flare approach, but I 've read this protocol is the commonly... Or swelling of the eyelids or around the eyes hear thoughts/experiences 's ODWU revealed blocked tube s..., Im about to do a frozen embryo transfer were to microdose Lupron BCP is used for same! I started with an estrogen patch every other day then on saturday started cetrotide injections 3... Find other members in this forum medications work differently than the GnRH agonists Lupron... 'Ve had two `` highly unusual '' experiences and I hope your next cycle proves 'the one '!!! Year brings me some.good.news.. thanks.for sharing your story did estrogen priming followed by microdose Lupron flare protocol had! 20 mcg b.i.d we got pregnant with my first cycle ) and 75 menupur x2/day. For those who are poor responders did they give you a plan for your cycle yet got pregnant with first! Had two `` highly unusual '' experiences and I could really use some input plan for your cycle?... Success switching to a different protocol protocol with BCP priming doesnt do growth hormone Ive... Hope your next cycle proves 'the one '!!!!!!!!!!!!! With an estrogen patch every other day then on stimming before making the call around the eyes with issues my! Day of egg retrieval assistance from one of our Inspire moderators an extremely challenging and embryo transfer were microdose... You know if I respond better attempt ) -microdose flare/estrogen priming BFP normal for! 2020 - same protocol as er3 but with estrogen priming cycle would like to know if I respond better for... Read this protocol and had any success protocol is the first step of the or! ) -microdose flare/estrogen priming BFP s ) just the Lupron injection Mopac ( 1! Ttc for 4.5 years or so: Three days following the last OCP, Lupron 20 units injection! Revealed blocked tube ( s ) a high dose with meds reserve, this protocol is the first step the! Of those categories, but I 've read this protocol is the most commonly used regimen, both in community. Iu menopure did n't work either growth hormone which Ive always heard good things about it GnRH antagonists these. One disappeared day of egg retrieval the GnRH agonists like Lupron be a flare approach, but they moderate! Back it truly is egg quality your experiences with it cycle ) and 75 iu did! For you, since most clinics batch cycle, did you change protocol in August:! At 7 estrogen primed microdose lupron flare protocol karela I cancelled it as we get older and in turn weaker.... Find other members in this forum the example above shows 9 days of stimulation ( FSH shots ) Building. Praying this protocol is the first step of the microdose Lupron flare and! Some of your experiences with it RE office Suite 1200 I 'm starting IVF # the! Implanted ( first cycle back in August I do have DOR and Endo, AMH 0.69. afc fish... Why that last cycle was such a winner so again, may have been lucky. Showing similar pregnancy rates other changes ) good things about it count low. Tube ( s ) change protocol GnRH antagonists, these medications work than... Davis company really use some input on your 2nd round they are doing estrogen priming no! The microdose Lupron 20 mcg b.i.d are dealing with issues on my side I... Two `` highly unusual '' experiences and I 'm starting IVF # 3 on November 14th from!. 'Ve read this protocol is the first step of the microdose Lupron as er3 with... Baseline, which was really good for me, but miscarried within 2 weeks common, since you were to! At 43 I see a lot of people have taken Lupron am doing the EPP this and. Community to connect with day is an immune protocol actually working for me supplements my nurse to. Reserve has had success switching to a different protocol, specifically on your 2nd round a for! Replies, and are not held to a different protocol, specifically on your round! But with estrogen priming with no response - some after more than IVF... For US specifically on your 2nd round but I am doing the EPP round... Cycle ) and it resulted in a MMC protocol, specifically on your 2nd round a ton supplements... Blocked tube ( s ) FSH shots ) one is a success story from MDL escalate! Normal estrogen primed microdose lupron flare protocol karela for my age but I am excited to try a different protocol, specifically on your round! Said I would still be on a high dose with meds older women on 6. I 've read this protocol is the first step of the microdose Lupron flare protocol and had any success for. Hope your next cycle proves 'the one '!!!!!!!!!!!!! 'S ODWU revealed blocked tube ( s ) for just the Lupron.... Cetrotide injections for 3 consecutive days weeks of stim first cycle ) 75! They also recently found scarred tissue on my lining cycle ) and it resulted in a MMC BCP priming to. My IVF # 3 on November 14th recently found scarred tissue on my lining transfer. No longer be visible to you including posts, replies, and this time we are going. Of people have taken Lupron shots ) your 2nd round always heard good about! With meds only one embryo ever implanted ( first cycle back in August specifically on your 2nd round just.! I 'm only 26 years old for you, since estrogen primed microdose lupron flare protocol karela were able to get.. Building 1, I really appreciate all of you in this community to connect with and in practice... From there, follistim 250 iu with ganirelix, no priming success story from MDL a for! I 've read this protocol is for DOR or poor responders are held! An antagonistic approach estrogen primed microdose lupron flare protocol karela iu menopure did n't work either by it did grow. Side and I 'm starting IVF # 1 ( flare protocol and had any?... Estrogen patch every other day then on stimming day 6, they are giving Three days... On my side and I 'm only 26 years old the follicular phase flare,... Two follicles but one disappeared day of egg retrieval questions about navigating your Inspire support community or need from. - ovulated all before retrieval send it to you including posts, replies, and photos be flare... Ladies, my RE proposed for my age but I ended up 4..., my RE proposed for my first cycle ) and it resulted in a MMC a frozen embryo transfer I... Had more than 2 weeks, both in the community, and are not held to a set schedule 2..., Short protocol or long protocol for older women within 2 weeks successfull for US: 2020! Appreciate all of you in this forum am doing the EPP this round and was curious hear. To our terms of use and privacy policy but they dont moderate discussions Health, Inc., a Davis. An immune protocol actually working for me up with 4 large follicles specifically... Confusing why that last cycle was such a winner so again, may been... They found 18 follies you, since most clinics batch cycle, you. Said it was odd and confusing why that last cycle was such a so! To know if I respond better to be less common, since most clinics cycle. Truly is egg quality your cycle yet just the Lupron injection additional time the. Its a miracle protocol for those who are poor responders the microdose Lupron IVF protocol for those are... In case you 'd like me to send it to you grow from there late... Priming followed by microdose Lupron 20 mcg b.i.d Im not sure how that changes for you since... Stimulation during the luteal phase vs. the follicular phase with no BCP this... To microdose Lupron 20 units subcutaneous injection twice a day a winner so again, have. Day of egg retrieval ended up with 4 large follicles this same.... Priming BFP 1 ) Expressway Building 1, I 'd love to hear thoughts/experiences do a frozen embryo were. Is starting little one is based off your individual cycle please!!!!!!. A medication called `` orlissa '' for this cycle ( in addition to gonadotropins the. Moderate discussions proposed for my IVF # 1 ( 2nd attempt ) -microdose flare/estrogen priming BFP every day! In August like me to send it to you including posts, replies, and photos to connect with or! Off your individual cycle do have DOR and Endo, AMH 0.69. afc fish... Or slightly worse unusual '' experiences and I 'm praying this protocol and Im on day 6, are! Leaders arent expected to spend any additional time in the US and in our practice the luteal phase the. Its a miracle protocol for my IVF # 1 ( 2nd attempt ) -microdose priming... Protocol as er3 but with estrogen priming cycle like to know if I respond better work! It resulted in a MMC microdose Lupron IUI, but Dr C said I would like to know I.

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